Product Code:	FMK001
Supplier Name:	R&D Systems Inc.
Size:	1 MG
Data Sheet:	View Data Sheet
Tags:	PROTEINS

Additional Details:	Caspase Inhibitor Z- (1 mg)
UNSPSC:	12352200

Sanyal A, Chen A, Nakayasu E, Lazar C, Zbornik E, Worby C, Koller A, Mattoo S A novel link between Fic (filamentation induced by cAMP)-mediated adenylylation/AMPylation and the unfolded protein response. J Biol Chem, 2015;290(13):8482-99. 2015 [PMID: 25601083] (Bioassay, Human).

Vucicevic L, Misirkic M, Janjetovic K, Harhaji-Trajkovic L, Prica M, Stevanovic D, Isenovic E, Sudar E, Sumarac-Dumanovic M, Micic D, Trajkovic V AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C. Biochem. Pharmacol., 2009;77(11):1684-93. 2009 [PMID: 19428322] (Flow, , Human).

Cheng YL, Lee SC, Lin SZ, Chang WL, Chen YL, Tsai NM, Liu YC, Tzao C, Yu DS, Harn HJ Anti-proliferative activity of Bupleurum scrozonerifolium in A549 human lung cancer cells in vitro and in vivo. Cancer Lett., 2005;222(2):183-93. 2005 [PMID: 15863267] (Human).

Hernandez-Corbacho M, Canals D, Adada M, Liu M, Senkal C, Yi J, Mao C, Luberto C, Hannun Y, Obeid L Tumor Necrosis Factor-alpha (TNFalpha)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death. J Biol Chem, 2015;290(42):25356-73. 2015 [PMID: 26318452] (Human).

Murata T, Tsuboi M, Hikita K, Kaneda N Protective effects of neurotrophic factors on tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of murine adrenal chromaffin cell line tsAM5D. J. Biol. Chem., 2006;281(32):22503-16. 2006 [PMID: 16772303] (Bioassay, Mouse).

Panzarini , Elisa, Inguscio , Valentin, Fimia , Gian Mar, Dini , Luciana Rose Bengal acetate photodynamic therapy (RBAc-PDT) induces exposure and release of Damage-Associated Molecular Patterns (DAMPs) in human HeLa cells. PLoS ONE, 2014;9(8):e105778. 2014 [PMID: 25140900] (Human).

Maqbool M, Imache M, Higgs M, Carmouse S, Pawlotsky J, Lerat H Regulation of hepatitis C virus replication by nuclear translocation of nonstructural 5A protein and transcriptional activation of host genes. J Virol, 2013;87(10):5523-39. 2013 [PMID: 23468497] (Human).

Park SJ, Kim MJ, Kim HB, Sohn HY, Bae JH, Kang CD, Kim SH Trichostatin A sensitizes human ovarian cancer cells to TRAIL-induced apoptosis by down-regulation of c-FLIPL via inhibition of EGFR pathway. Biochem. Pharmacol., 2009;77(8):1328-36. 2009 [PMID: 19426671] (Bioassay, Human).

Braun F, Mathur R, Sehgal L, Wilkie-Grantham R, Chandra J, Berkova Z, Samaniego F Inhibition of methyltransferases accelerates degradation of cFLIP and sensitizes B-cell lymphoma cells to TRAIL-induced apoptosis. PLoS ONE, 2015;10(3):e0117994. 2015 [PMID: 25738497] (Human).

Petit I, Karajannis MA, Vincent L, Young L, Butler J, Hooper AT, Shido K, Steller H, Chaplin DJ, Feldman E, Rafii S The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death. Blood, 2007;111(4):1951-61. 2007 [PMID: 18024794] (Bioassay, Human).

Chung K, Park H, Jung S, Ha S, Yoo S, Woo H, Lee H, Kim S, Kim E, Moon C, Yu S Calpain Determines the Propensity of Adult Hippocampal Neural Stem Cells to Autophagic Cell Death Following Insulin Withdrawal. Stem Cells, 2015;33(10):3052-64. 2015 [PMID: 26086870] (Rat).

Tanaka R, Tomosugi M, Horinaka M, Sowa Y, Sakai T Metformin Causes G1-Phase Arrest via Down-Regulation of MiR-221 and Enhances TRAIL Sensitivity through DR5 Up-Regulation in Pancreatic Cancer Cells. PLoS ONE, 2015;10(5):e0125779. 2015 [PMID: 25955843] (Human).

Chakravarthi B, Sujay R, Kuriakose G, Karande A, Jayabaskaran C Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and its precursor baccatin III purified from endophytic Fusarium solani. Cancer Cell Int, 2013;13(1):105. 2013 [PMID: 24152585] (Human).

Horinaka , Mano, Yoshida , Tatsushi, Tomosugi , Mitsuhir, Yasuda , Shusuke, Sowa , Yoshihir, Sakai , Toshiyuk Myeloid zinc finger 1 mediates sulindac sulfide-induced upregulation of death receptor 5 of human colon cancer cells. Sci Rep, 2014;4(0):6000. 2014 [PMID: 25102912] (Bioassay, Human).

Singer B, Opp L, Heinrich A, Schreiber F, Binding-Liermann R, Berrocal-Almanza L, Heyl K, Muller M, Weimann A, Zweigner J, Slevogt H Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses. PLoS ONE, 2014;9(4):e94106. 2014 [PMID: 24743304] (Bioassay, Human).

Jang , Jae Youn, Kim , Seong-Ju, Cho , Eun Kyun, Jeong , Soung Wo, Park , Eui Ju, Lee , Woong Ch, Lee , Sae Hwan, Kim , Sang Gyu, Kim , Young Se, Kim , Hong Soo, Kim , Boo Sung, Lin , Wenyu, Chung , Raymond TRAIL enhances apoptosis of human hepatocellular carcinoma cells sensitized by hepatitis C virus infection: therapeutic implications. PLoS ONE, 2014;9(6):e98171. 2014 [PMID: 24927176] (Bioassay, Human).

Yamashita H, Nakamura T, Takahashi T, Nagano Y, Hiji M, Hirabayashi T, Amano T, Yagi T, Sakai N, Kohriyama T, Matsumoto M Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death. J. Neurochem., 2006;98(1):45-56. 2006 [PMID: 16805795] (Mouse).

Callaway J, Smith S, Widman D, McKinnon K, Scholle F, Sempowski G, Dittmer D, Crowe J, de Silva A, Ting J Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1beta Secretion: A Primary Human Monocyte Model. PLoS ONE, 2015;10(8):e0136708. 2015 [PMID: 26301593] (Human).

Mhaidat N, Bouklihacene M, Thorne R 5-Fluorouracil-induced apoptosis in colorectal cancer cells is caspase-9-dependent and mediated by activation of protein kinase C-delta Oncol Lett, 2014;8(2):699-704. 2014 [PMID: 25013487] (Bioassay, Human).

Martelli M, Gionfriddo I, Mezzasoma F, Milano F, Pierangeli S, Mulas F, Pacini R, Tabarrini A, Pettirossi V, Rossi R, Vetro C, Brunetti L, Sportoletti P, Tiacci E, Di Raimondo F, Falini B Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells. Blood, 2015;125(22):3455-65. 2015 [PMID: 25795919] (Bioassay, Human).

Wang , Wei, Zhou , Aie, Zhang , Xuemei, Xiang , Yun, Huang , Yifei, Wang , Lei, Zhang , Shuai, Liu , Yusi, Yin , Yibing, He , Yujuan Interleukin 17A promotes pneumococcal clearance by recruiting neutrophils and inducing apoptosis through a p38 mitogen-activated protein kinase-dependent mechanism in acute otitis media. Infect Immun, 2014;82(6):2368-77. 2014 [PMID: 24664502] (In Vivo, Mouse).

Mukherjee P, Woods T, Moore R, Peterson K Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death. Immunity, 2013;38(4):705-16. 2013 [PMID: 23499490] (Bioassay, Mouse).

Ladewig J, Koch P, Endl E, Meiners B, Opitz T, Couillard-Despres S, Aigner L, Brustle O Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons. Stem Cells, 2008;26(7):1705-12. 2008 [PMID: 18420830] (Bioassay, Human).

Edgeworth JD, Spencer J, Phalipon A, Griffin GE, Sansonetti PJ Cytotoxicity and interleukin-1beta processing following Shigella flexneri infection of human monocyte-derived dendritic cells. Eur. J. Immunol., 2002;32(5):1464-71. 2002 [PMID: 11981835] (Human).

Yang Z, Balic A, Michon F, Juuri E, Thesleff I Mesenchymal Wnt/beta-Catenin Signaling Controls Epithelial Stem Cell Homeostasis in Teeth by Inhibiting the Antiapoptotic Effect of Fgf10. Stem Cells, 2015;33(5):1670-81. 2015 [PMID: 25693510] (Mouse).

Bielaszewska M, Ruter C, Kunsmann L, Greune L, Bauwens A, Zhang W, Kuczius T, Kim K, Mellmann A, Schmidt M, Karch H Enterohemorrhagic Escherichia coli hemolysin employs outer membrane vesicles to target mitochondria and cause endothelial and epithelial apoptosis. PLoS Pathog, 2013;9(12):e1003797. 2013 [PMID: 24348251] (Human).

Shi Y, Nikulenkov F, Zawacka-Pankau J, Li H, Gabdoulline R, Xu J, Eriksson S, Hedstrom E, Issaeva N, Kel A, Arner E, Selivanova G ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis. Cell Death Differ, 2014;21(4):612-23. 2014 [PMID: 24413150] (Bioassay, Human).

Jin , Yunyun, Xu , Jinjin, Yin , Meng-Xin, Lu , Yi, Hu , Lianxin, Li , Peixue, Zhang , Peng, Yuan , Zengqian, Ho , Margaret, Ji , Hongbin, Zhao , Yun, Zhang , Lei Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling. Elife, 2013;2(0):e00999. 2013 [PMID: 24137538] (Drosophila).

McCloy R, Shelley E, Roberts C, Boslem E, Biden T, Nicholson R, Gee J, Sutherland R, Musgrove E, Burgess A, Butt A Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells. Br J Cancer, 2013;109(12):3034-41. 2013 [PMID: 24178758] (cell culture, Human).

Magnifico S, Saias L, Deleglise B, Duplus E, Kilinc D, Miquel M, Viovy J, Brugg B, Peyrin J NAD+ acts on mitochondrial SirT3 to prevent axonal caspase activation and axonal degeneration. FASEB J, 2013;27(12):4712-22. 2013 [PMID: 23975935] (Mouse).

Park SJ, Kim MJ, Kim HB, Kang CD, Kim SH Sensitization of imatinib-resistant CML cells to TRAIL-induced apoptosis is mediated through down-regulation of Bcr-Abl as well as c-FLIP. Biochem. J., 2009;420(1):73-81. 2009 [PMID: 19203346] (Human).

Bulau A, Nold M, Li S, Nold-Petry C, Fink M, Mansell A, Schwerd T, Hong J, Rubartelli A, Dinarello C, Bufler P Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses. Proc Natl Acad Sci U S A, 2014;111(7):2650-5. 2014 [PMID: 24481253] (Bioassay, Mouse).

Kaushik , Neha, Lee , Su Jae, Choi , Tae Gyu, Baik , Ku Youn, Uhm , Han Sup, Kim , Chung Hy, Kaushik , Nagendra, Choi , Eun Ha Non-thermal plasma with 2-deoxy-D-glucose synergistically induces cell death by targeting glycolysis in blood cancer cells. Sci Rep, 2015;5(0):8726. 2015 [PMID: 25735798] (Human).

Son KN, Becker RP, Kallio P, Lipton HL Theiler's virus-induced intrinsic apoptosis in M1-D macrophages is Bax mediated and restricts virus infectivity: a mechanism for persistence of a cytolytic virus. J. Virol., 2008;82(9):4502-10. 2008 [PMID: 18287228] (Mouse).

Plachta N, Annaheim C, Bissiere S, Lin S, Ruegg M, Hoving S, Muller D, Poirier F, Bibel M, Barde YA Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells. Nat. Neurosci., 2007;10(6):712-9. 2007 [PMID: 17486104] (Mouse).

Park EJ, Zhao YZ, Kim YC, Sohn DH Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts. Eur. J. Pharmacol., 2007;559(2):115-23. 2007 [PMID: 17292878] (Bioassay, Mouse).

Tanaka N, Patel A, Wang J, Frederick M, Kalu N, Zhao M, Fitzgerald A, Xie T, Silver N, Caulin C, Zhou G, Skinner H, Johnson F, Myers J, Osman A Wee-1 Kinase Inhibition Sensitizes High-Risk HPV+ HNSCC to Apoptosis Accompanied by Downregulation of MCl-1 and XIAP Antiapoptotic Proteins. Clin Cancer Res, 2015;21(21):4831-44. 2015 [PMID: 26124202] (Human).

Zhang , Xiangnan, Yan , Haijing, Yuan , Yang, Gao , Jieqiong, Shen , Zhe, Cheng , Yun, Shen , Yao, Wang , Rong-Ron, Wang , Xiaofen, Hu , Wei-Wei, Wang , Guanghui, Chen , Zhong Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance. Autophagy, 2013;9(9):1321-33. 2013 [PMID: 23800795] (Inhibitor, Rat).

Furukawa Y, Nishimura N, Furukawa Y, Satoh M, Endo H, Iwase S, Yamada H, Matsuda M, Kano Y, Nakamura M Apaf-1 is a mediator of E2F-1-induced apoptosis. J. Biol. Chem., 2002;277(42):39760-8. 2002 [PMID: 12149244] (Human).

Koto K, Murata H, Kimura S, Sawai Y, Horie N, Matsui T, Ryu K, Ashihara E, Maekawa T, Kubo T, Fushiki S Zoledronic acid significantly enhances radiationinduced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signaling. Int J Oncol, 2013;42(2):525-34. 2013 [PMID: 23242142] (Bioassay, Human).

Xi , Xueyan, Zhang , Xiaoyan, Wang , Bei, Wang , Tao, Wang , Ji, Huang , He, Wang , Jianwei, Jin , Qi, Zhao , Zhendong The interplays between autophagy and apoptosis induced by enterovirus 71. PLoS ONE, 2013;8(2):e56966. 2013 [PMID: 23437282] (Human).

Ikner A, Ashkenazi A TWEAK Induces Apoptosis through a Death-signaling Complex Comprising Receptor-interacting Protein 1 (RIP1), Fas-associated Death Domain (FADD), and Caspase-8. J. Biol. Chem., 2011;286(24):21546-54. 2011 [PMID: 21525013] (Human).

Choi , Eun-Sun, Nam , Jeong-Se, Jung , Ji-Youn, Cho , Nam-Pyo, Cho , Sung-Dae Modulation of specificity protein 1 by mithramycin A as a novel therapeutic strategy for cervical cancer. Sci Rep, 2014;4(0):7162. 2014 [PMID: 25418289] (Bioassay, Human).

K Vorá?ová, J Hájek, J Mareš, P Urajová, M Kuzma, J Cheel, A Villunger, A Kapuscik, M Bally, P Novák, M Kabelá?, G Krumschnab, M Lukeš, L Voloshko, J Kopecký, P Hrouzek The cyanobacterial metabolite nocuolin a is a natural oxadiazine that triggers apoptosis in human cancer cells PLoS ONE, 2017;12(3):e0172850. 2017 [PMID: 28253280] (Bioassay, Human).

Mongiat M, Ligresti G, Marastoni S, Lorenzon E, Doliana R, Colombatti A Regulation of the extrinsic apoptotic pathway by the extracellular matrix glycoprotein EMILIN2. Mol. Cell. Biol., 2007;27(20):7176-87. 2007 [PMID: 17698584] (Human).

Aguzzi MS, Giampietri C, De Marchis F, Padula F, Gaeta R, Ragone G, Capogrossi MC, Facchiano A RGDS peptide induces caspase 8 and caspase 9 activation in human endothelial cells. Blood, 2004;103(11):4180-7. 2004 [PMID: 14982875] (Human).

Wang , Jian-Gan, Zheng , Xing-Xin, Zeng , Guang-Ya, Zhou , Ying-Jun, Yuan , Hong Purified vitexin compound 1 induces apoptosis through activation of FOXO3a in hepatocellular carcinoma. Oncol Rep, 2014;31(1):488-96. 2014 [PMID: 24247909].

Yang H, Cai H, Wan L, Liu S, Li S, Cheng J, Lu X Bombesin analogue-mediated delivery preferentially enhances the cytotoxicity of a mitochondria-disrupting peptide in tumor cells. PLoS ONE, 2013;8(2):e57358. 2013 [PMID: 23451211] (Human).

Lamothe B, Lai Y, Xie M, Schneider M, Darnay B TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis. Mol Cell Biol, 2013;33(3):582-95. 2013 [PMID: 23166301] (Mouse).

Lee SC, Chan J, Clement MV, Pervaiz S Functional proteomics of resveratrol-induced colon cancer cell apoptosis: caspase-6-mediated cleavage of lamin A is a major signaling loop. Proteomics, 2006;6(8):2386-94. 2006 [PMID: 16518869] (Human).

Mueller-Ortiz S, Morales J, Wetsel R The receptor for the complement C3a anaphylatoxin (C3aR) provides host protection against Listeria monocytogenes-induced apoptosis. J Immunol, 2014;193(3):1278-89. 2014 [PMID: 24981453] (Mouse).

Lei , Y, Henderson , B R, Emmanuel , C, Harnett , P R, deFazio , A Inhibition of ANKRD1 sensitizes human ovarian cancer cells to endoplasmic reticulum stress-induced apoptosis. Oncogene, 2015;34(4):485-95. 2015 [PMID: 24531715] (Human).

Knockdown of RIPK1 Markedly Exacerbates Murine Immune-Mediated Liver Injury through Massive Apoptosis of Hepatocytes, Independent of Necroptosis and Inhibition of NF-?B J Immunol, 2016;0(0):. 2016 [PMID: 27605011] (In Vivo, Mouse).

Karrar A, Broome U, Uzunel M, Qureshi AR, Sumitran-Holgersson S Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction. Gut, 2006;56(2):243-52. 2006 [PMID: 16840505] (Human).

Liang X, Moseman EA, Farrar MA Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells. Blood, 2010;115(24):5041-52. 2010 [PMID: 20339095] (Human).

D'Agnillo , Felice, Williams , Matthew, Moayeri , Mahtab, Warfel , Jason M Anthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctions. PLoS ONE, 2013;8(4):e62576. 2013 [PMID: 23626836] (Human).

French R, Hayward O, Jones S, Yang W, Clarkson R Cytoplasmic levels of cFLIP determine a broad susceptibility of breast cancer stem/progenitor-like cells to TRAIL. Mol Cancer, 2015;14(0):209. 2015 [PMID: 26667821] (Human).

Thompson CK, Brenowitz EA Caspase inhibitor infusion protects an avian song control circuit from seasonal-like neurodegeneration. J. Neurosci., 2008;28(28):7130-6. 2008 [PMID: 18614682] (Avian- Gambels White Crowned Sparrows).

Virard F, Cousty S, Cambus J, Valentin A, Kemoun P, Clement F Cold Atmospheric Plasma Induces a Predominantly Necrotic Cell Death via the Microenvironment. PLoS ONE, 2015;10(8):e0133120. 2015 [PMID: 26275141] (Human).

Targeted inhibition of Polo-like kinase 1 by a novel small-molecule inhibitor induces mitotic catastrophe and apoptosis in human bladder cancer cells J. Cell. Mol. Med, 2016;0(0):. 2016 [PMID: 27878946] (Bioassay, Human).

Tsai WS, Yeow WS, Chua A, Reddy RM, Nguyen DM, Schrump DS Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin. Mol. Cancer Ther., 2006;5(12):2977-90. 2006 [PMID: 17172403] (Human).

Marie-Claude Gaudreau Heterogeneous Nuclear Ribonucleoprotein L is required for the survival and functional integrity of murine hematopoietic stem cells Sci Rep, 2016;6(0):27379. 2016 [PMID: 27271479] (Bioassay, Mouse).

Anders , Corina, Ashton , Nick, Ranjzad , Parisa, Dilworth , Mark R, Woolf , Adrian S Ex vivo modeling of chemical synergy in prenatal kidney cystogenesis. PLoS ONE, 2013;8(3):e57797. 2013 [PMID: 23554868] (Mouse).

Sanz R, Ferraro G, Fournier A IgLON cell adhesion molecules are shed from the cell surface of cortical neurons to promote neuronal growth. J Biol Chem, 2015;290(7):4330-42. 2015 [PMID: 25538237] (Rat).

Li C, Liu Y, Chen Y, Yu D, Williams K, Liu M Novel proteolytic microvesicles released from human macrophages after exposure to tobacco smoke. Am J Pathol, 2013;182(5):1552-62. 2013 [PMID: 23499464] (Human).

Park W Anti-apoptotic effect of caspase inhibitors on H(2)O(2)-treated HeLa cells through early suppression of its oxidative stress. Oncol Rep, 2014;31(5):2413-21. 2014 [PMID: 24627148] (Bioassay, Human).

You B, Park W Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels. Int J Oncol, 2014;44(5):1745-55. 2014 [PMID: 24626405] (Human).

Liu B, Meng D, Wei T, Zhang S, Hu Y, Wang M Apoptosis and pro-inflammatory cytokine response of mast cells induced by influenza A viruses. PLoS ONE, 2014;9(6):e100109. 2014 [PMID: 24923273] (Mouse).

RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress PLoS ONE, 2016;11(12):e0168641. 2016 [PMID: 27992599] (Bioassay, Primate - Chlorocebus pygerythrus (African Green Monkey)).

Teigler J, Kagan J, Barouch D Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity. J Virol, 2014;88(18):10354-63. 2014 [PMID: 24991003] (Human).

Anti-apoptotic Effects of Human Wharton's Jelly-derived Mesenchymal Stem Cells on Skeletal Muscle Cells Mediated via Secretion of XCL1 Mol Ther, 2016;0(0):. 2016 [PMID: 27434589] (Bioassay, Mouse).

You B, Shin H, Park W PX-12 inhibits the growth of A549 lung cancer cells via G2/M phase arrest and ROS-dependent apoptosis. Int J Oncol, 2014;44(1):301-8. 2014 [PMID: 24172913] (Human).

Han B, You B, Park W Valproic acid inhibits the growth of HeLa cervical cancer cells via caspase-dependent apoptosis. Oncol Rep, 2013;30(6):2999-3005. 2013 [PMID: 24064712] (Bioassay, Human).

Hepatitis C Virus Infection of Cultured Human Hepatoma Cells Causes Apoptosis and Pyroptosis in Both Infected and Bystander Cells Sci Rep, 2016;6(0):37433. 2016 [PMID: 27974850] (Bioassay, Human).

New derivatives of the antimalarial drug Pyrimethamine in the control of melanoma tumor growth: an in vitro and in vivo study J Exp Clin Cancer Res, 2016;35(1):137. 2016 [PMID: 27599543] (Human).

Shin H, You B, Park W PX-12-induced HeLa cell death is associated with oxidative stress and GSH depletion. Oncol Lett, 2013;6(6):1804-1810. 2013 [PMID: 24260080] (Bioassay, Human).

Sorg H, Krueger C, Schulz T, Menger MD, Schmitz F, Vollmar B Effects of erythropoietin in skin wound healing are dose related. FASEB J., 2009;23(9):3049-58. 2009 [PMID: 19403513] (Mouse).

A Subpopulation of the K562 Cells Are Killed by Curcumin Treatment after G2/M Arrest and Mitotic Catastrophe PLoS ONE, 2016;11(11):e0165971. 2016 [PMID: 27832139] (Bioassay, Human).

Multiple Active Compounds from Viscum album L. Synergistically Converge to Promote Apoptosis in Ewing Sarcoma PLoS ONE, 2016;11(9):e0159749. 2016 [PMID: 27589063] (Bioassay, Human).

Jing Fang A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes Nat Med, 2016;0(0):. 2016 [PMID: 27294874] (Bioassay, Human).

Induction of apoptosis by Armillaria mellea constituent armillarikin in human hepatocellular carcinoma Onco Targets Ther, 2016;9(0):4773-83. 2016 [PMID: 27536140] (Bioassay, Human).

Attali G, Gancz D, Fishelson Z Increased sensitivity of early apoptotic cells to complement-mediated lysis. Eur. J. Immunol., 2004;34(11):3236-45. 2004 [PMID: 15368275] (Human).

Lapatinib induces autophagic cell death and differentiation in acute myeloblastic leukemia Onco Targets Ther, 2016;9(0):4453-64. 2016 [PMID: 27499639] (Bioassay, Human).

Salaun B, Coste I, Rissoan MC, Lebecque SJ, Renno T TLR3 can directly trigger apoptosis in human cancer cells. J. Immunol., 2006;176(8):4894-901. 2006 [PMID: 16585585] (Human).

Kim , Min-Jung, Yoo , Joo-Yeon Active caspase-1-mediated secretion of retinoic acid inducible gene-I. J Immunol, 2008;181(10):7324-31. 2008 [PMID: 18981155] (Bioassay, Human).

dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8. Cell Death Differ., 2012;19(9):1482-94. 2012 [PMID: 22421964] (Human).

Schindler A, Foley E Hexokinase 1 blocks apoptotic signals at the mitochondria. Cell Signal, 2013;25(12):2685-92. 2013 [PMID: 24018046] (Bioassay, Human).

O Arizmendi, WD Picking, WL Picking Macrophage Apoptosis Triggered by IpaD from Shigella flexneri Infect Immun, 2016;0(0):. 2016 [PMID: 27068089] (Mouse).

Imbeault E, Mahvelati T, Braun R, Gris P, Gris D Nlrx1 regulates neuronal cell death. Mol Brain, 2014;7(0):90. 2014 [PMID: 25540124] (Mouse).