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Complement Factor B Antibodies

Complement Factor B Antibodies


  • Complement Factor B

    Complement factor B is an immune system protein that plays a major role in the alternative complement pathway. Factor B binds C3b in a Mg2+ dependent manner at the antigenic surface. This interaction exposes a site on factor B that serves as a substrate for the serum protease factor D. Factor D cleaves factor B bound to C3b, releasing a small fragment (Ba) and generating C3bBb. The resulting C3bBb complex has C3 convertase activity analogous to the C4b2a complex of the classical pathway. The C3 convertase enhances the processing of C3 leading to a marked increase in the number of C3b molecules deposited on the antigenic surface. This leads to the generation of the C3bBb3b complex, which exhibits C5 convertase activity, analogous to the C4b2a3b complex in the classical pathway. This is the convergence point of both the classical and alternative complement pathways.
       
Product Name: Anti-Human Complement Factor B/Ba, Purified (clone: P21/15), (Mouse IgG2a K)
Code:
CL7618AP
Supplier:
Cedarlane
Size:
200 ug
Unit Price:
$371.00 CDN
Product Name: Anti-Human Complement Factor B/Ba, Biotin (clone: P21/15), (Mouse IgG2a K)
Code:
CL7618B
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$254.00 CDN
Product Name: Anti-Human Complement Factor B/Ba, FITC (clone: P21/15), (Mouse IgG2a K)
Code:
CL7618F
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$273.00 CDN
Product Name: Anti-Human Complement Factor B/Ba, PE (clone: P21/15), (Mouse IgG2a K)
Code:
CL7618PE
Supplier:
Cedarlane
Size:
50 ug
Unit Price:
$223.00 CDN
Product Name: Anti-Human Complement Factor B/Bb, Purified (clone: M13/12), (Mouse IgG1 K)
Code:
CL7619AP
Supplier:
Cedarlane
Size:
200 ug
Unit Price:
$371.00 CDN
Product Name: Anti-Human Complement Factor B/Bb, Biotin (clone: M13/12), (Mouse IgG1 K)
Code:
CL7619B
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$254.00 CDN
Product Name: Anti-Human Complement Factor B/Bb, FITC (clone: M13/12), (Mouse IgG1 K)
Code:
CL7619F
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$273.00 CDN
Product Name: Anti-Human Complement Factor B/Bb, PE (clone: M13/12), (Mouse IgG1 K)
Code:
CL7619PE
Supplier:
Cedarlane
Size:
50 ug
Unit Price:
$207.00 CDN

Custom Antibody Services

CEDARLANE® manufactures complement, Lympholyte® cell separation media, cell purification immunocolumns, neuronal cell lines and a wide range of antibodies. CEDARLANE® continues to offer our Custom Antibody Services and increased demand has lead to the continued expansion of our facility. We understand the varied nature of custom work and encourage you to call our qualified staff to discuss the details of your project. Please inquire about other services not listed. Be assured that we at CEDARLANE® are dedicated to ensuring the confidentiality of all projects we discuss.