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Cedarlane › Reagents › Cedarlane Manufactured › Reagents For Mouse › Miscellaneous Antibodies › Mac-3 (CD107b) › M3/84

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Custom Antisera

CEDARLANE® manufactures Complement, Lympholyte® cell separation media, cell purification Immunocolumns and a wide range of Antibodies. Also, CEDARLANE® continues to offer our Custom Antibody Services.

  

Cedarlane-manufactured Reagents

Our line of Cedarlane-manufactured reagents.

M3/84

  • Description

    Cedarlane’s anti-mouse MAC-3 monoclonal antibody recognizes the MAC-3 antigen which is found on macrophages and some nonlymphoid tissues, but not on lymphocytes. It is a glycoprotein showing a broad band in SDS-PAGE, and is synthesized by macrophages (average molecular weight 92-110,000 daltons, depending on the origin of macrophages).
    It reacts with peritoneal exudate macrophages where the exudate is provoked by thioglycollate, protease peptone, L. monocytogenes, lipopolysaccharide and concanavalin A. It does not react with thymocytes, spleen, lymph node or bone marrow cells in immunofluorescent flow cytometry.
     MAC-3 is a general marker for macrophages and can be used to distinguish these cells from lymphocytes. Its Mw and cell distribution differentiate MAC-3 from MAC-2 and MAC-1 antigens.
    ______________________________________________________________________________________________________

    Flow Cytometry Analysis
    Thioglycolate-elicited C57BL/6 mouse peritoneal macrophages were stained with anti-Mac-3 (clone: M3/84) (filled histogram) or rat IgG1 isotype control (open histogram).
       
Product Name: Anti-Mouse Mac-3, Alexa Fluor®488 (Clone M3/84) (rat IgG1)
Code:
CL8943AF4
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$369.00 CDN
Product Name: Anti-Mouse Mac-3, Purified (Clone M3/84) (rat IgG1)
Code:
CL8943AP
Supplier:
Cedarlane
Size:
100ug
Unit Price:
$258.00 CDN
Product Name: Anti-Mouse Mac-3, Purified (Clone M3/84) (rat IgG1)
Code:
CL8943AP-3
Supplier:
Cedarlane
Size:
300ug
Unit Price:
$613.00 CDN
Product Name: Anti-Mouse Mac-3, Biotin (Clone M3/84) (rat IgG1)
Code:
CL8943B
Supplier:
Cedarlane
Size:
100ug
Unit Price:
$348.00 CDN
Product Name: Anti-Mouse Mac-3, Biotin (Clone M3/84) (rat IgG1)
Code:
CL8943B-3
Supplier:
Cedarlane
Size:
300ug
Unit Price:
$908.00 CDN
Product Name: Anti-Mouse Mac-3, FITC (Clone M3/84) (rat IgG1)
Code:
CL8943F
Supplier:
Cedarlane
Size:
100ug
Unit Price:
$348.00 CDN
Product Name: Anti-Mouse Mac-3, FITC (Clone M3/84) (rat IgG1)
Code:
CL8943F-3
Supplier:
Cedarlane
Size:
300ug
Unit Price:
$823.00 CDN
Product Name: Anti-Mouse Mac-3, PE (Clone M3/84) (rat IgG1)
Code:
CL8943PE
Supplier:
Cedarlane
Size:
50ug
Unit Price:
$308.00 CDN
Product Name: Anti-Mouse Mac-3, PE (Clone M3/84) (rat IgG1)
Code:
CL8943PE-3
Supplier:
Cedarlane
Size:
300ug
Unit Price:
$749.00 CDN

  • References

    1)  Springer, T.A. (1981). Monoclonal Antibody Analysis of Complex Biological Systems. J. Bio/. Chem. 256:3833-3839.

    2)  Knisley, K.A. and Weitlauf, H.M. (1993). Compartmentalized reactivity of M3/38 (anti-Mac-2) and M3/84 (anti-Mac-3) in the uterus of pregnant mice. Journal of Reproduction and Fertility. 97:521-527

    3)  Ho, M.K. and Springer, T.A. (1983). Tissue distribution, Structural Characterization, and Biosynthesis of Mac-3, a Macrophage Surface Glycoprotein Exhibiting Molecular Weight Heterogeneity. Journal of Biological Chemistry. 258:636-642.

Custom Antibody Services

CEDARLANE® manufactures complement, Lympholyte® cell separation media, cell purification immunocolumns, neuronal cell lines and a wide range of antibodies. CEDARLANE® continues to offer our Custom Antibody Services and increased demand has lead to the continued expansion of our facility. We understand the varied nature of custom work and encourage you to call our qualified staff to discuss the details of your project. Please inquire about other services not listed. Be assured that we at CEDARLANE® are dedicated to ensuring the confidentiality of all projects we discuss.



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