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OX-30

  • Description

    Cedarlane's anti-rat CD45 monoclonal antibody recognizes a monomorphic determinant of the rat leukocyte common antigen (1). The antigen recognized is a heavily glycosylated membrane glycoprotein of molecular weight 170,000 Da on thymocytes but molecular weight 170,000-220,000 Da on other leukocytes. The leukocyte common antigen (L-CA) is a major glycoprotein of haematopoietic cells but is not found on other tissues or erythroid cells.  It is present on greater than 95% of thymocytes, bone marrow cells and thoracic duct lymphocytes. This molecule carries much of the carbohydrate of thymocytes and shows interesting heterogeneity amongst T lymphocytes and B lymphocytes (2,3).
    This antibody is suitable for use in flow cytometry and immunohistochemistry with frozen sections. This clone has also been reported to be unsuitable for use with paraffin sections.
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    Flow Cytometry Analysis
    Wistar rat thymocytes were stained with anti-CD45 (clone: OX-30) (filled histogram) or mouse IgG2a isotype control (open histogram).
       
Product Name: Anti-Rat CD45 Ascites (Clone OX-30) (mouse IgG2a)
Code:
CL001A
Supplier:
Cedarlane
Size:
0.5ml
Unit Price:
$520.00 CDN
Product Name: Anti-Rat CD45 Purified (Clone OX-30) (mouse IgG2a)
Code:
CL001AP
Supplier:
Cedarlane
Size:
250ug
Unit Price:
$227.00 CDN
Product Name: Anti-Rat CD45 Purified (Clone OX-30) (mouse IgG2a)
Code:
CL001AP-2
Supplier:
Cedarlane
Size:
500ug
Unit Price:
$396.00 CDN
Product Name: Anti-Rat CD45 Biotin (Clone OX-30) (mouse IgG2a)
Code:
CL001B
Supplier:
Cedarlane
Size:
100ug
Unit Price:
$218.00 CDN
Product Name: Anti-Rat CD45 Biotin (Clone OX-30) (mouse IgG2a)
Code:
CL001B-5
Supplier:
Cedarlane
Size:
500ug
Unit Price:
$487.00 CDN
Product Name: Anti-Rat CD45 FITC (Clone OX-30) (mouse IgG2a)
Code:
CL001F
Supplier:
Cedarlane
Size:
100ug
Unit Price:
$218.00 CDN
Product Name: Anti-Rat CD45 FITC (Clone OX-30) (mouse IgG2a)
Code:
CL001F-5
Supplier:
Cedarlane
Size:
500ug
Unit Price:
$650.00 CDN
Product Name: Anti-Rat CD45 No Azide (Clone OX-30) (mouse IgG2a)
Code:
CL001NA
Supplier:
Cedarlane
Size:
1mg
Unit Price:
$688.00 CDN
Product Name: Anti-Rat CD45 PE (Clone OX-30) (mouse IgG2a)
Code:
CL001PE
Supplier:
Cedarlane
Size:
50ug
Unit Price:
$224.00 CDN
Product Name: Anti-Rat CD45 PE (Clone OX-30) (mouse IgG2a)
Code:
CL001PE-4
Supplier:
Cedarlane
Size:
200ug
Unit Price:
$630.00 CDN
  • References

    1)  Sunderland,C.A., McMaster, W.R., and A.F. Williams. (1979) Eur. J.Immunol. 9, 155-159. Purification with monoclonal antibody of a predominant leukocyte-common antigen and glycoprotein from rat thymocytes.

    2)  Brown, W.R.A., Barclay,A.N., Sunderland, C.A. and A.F. Williams. (1981) Nature. 289, 1164-1177. Identification of a glycoprotein-like molecule at the cell surface of rat thymocytes.

    3)  Standring, R. and A.F. Williams. (1978) Biochim.Biophys. Acta. 508, 85-96. Glycoproteins and antigens of membranes prepared from rat thymocytes after lysis by shearing or with the detergent Tween-40.

    4)  Brown, W.R.A. and A.F. Williams. (1982)  Immunology. 46, 713-726. Lymphocyte cell surface glycoproteins which bind to soybean and peanut lectins.

    5)  Woollet, G.R., Barclay, A.N., Puklavec, M. and A.F. Williams. (1985) Eur. J. Immunol. 15, 168-173. Molecular and antigenic heterogeneity of the rat leukocyte-common antigen from thymocytes and T and B lymphocytes.

    6)  Brouard, S., et al.  (1999)  J. of Immunol. 162, 3367-3377. T Cell repertoire alterations of vascularized xenografts.

Custom Antibody Services

CEDARLANE® manufactures complement, Lympholyte® cell separation media, cell purification immunocolumns, neuronal cell lines and a wide range of antibodies. CEDARLANE® continues to offer our Custom Antibody Services and increased demand has lead to the continued expansion of our facility. We understand the varied nature of custom work and encourage you to call our qualified staff to discuss the details of your project. Please inquire about other services not listed. Be assured that we at CEDARLANE® are dedicated to ensuring the confidentiality of all projects we discuss.



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