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Cedarlane › Reagents › Cedarlane Manufactured › Reagents For Human › CD Antibodies › CD45R › YTH 80.103

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YTH 80.103

  • Description

    Cedarlane’s anti-Human CD45R monoclonal antibody specifically binds to human CD45R. This is the longest isoform of the human leucocyte common antigen, CD45. CD45 is a family of single-chain transmembrane glycoproteins with protein phosphatase activity involved in transmembrane signaling. The molecular weight of CD45R is dependent on its level of glycosylation, which varies from its sources of expression: 200 kDa from T cells, 220 kDa from B cells as well as certain activated T cells and other antigen presenting cells. Recognition of antigen may be dependent on expression levels of sialic acid.
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    Flow Cytometry Analysis
    Human peripheral blood lymphocytes were stained with anti-CD45R (clone: YTH 80.103) (filled histogram) or Rat IgG2b isotype control (open histogram).
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    Immunofluorescence Analysis


    Purified Anti-Human CD45R (CL7606AP) staining of paraformaldehyde-fixed paraffin-embedded human spleen sections at 400x magnification with DAPI counterstain. (Rat anti-human CD45R (CL7606AP) 1:500; Alexa Fluor 488 Goat anti-rat 1:500 (Molecular Probes) and Normal Goat Serum (blocking))
       
Product Name: Anti-Human (CD45R), Alexa Fluor®488 (clone YTH 80.103), (Rat IgG2b)
Code:
CL7606AF4
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$398.00 CDN
Product Name: Anti-Human (CD45R), Purified (clone YTH 80.103), (Rat IgG2b)
Code:
CL7606AP
Supplier:
Cedarlane
Size:
200 ug
Unit Price:
$496.00 CDN
Product Name: Anti-Human (CD45R), APC (clone YTH 80.103), (Rat IgG2b)
Code:
CL7606APC
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$570.00 CDN
Product Name: Anti-Human (CD45R), Biotin (clone YTH 80.103), (Rat IgG2b)
Code:
CL7606B
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$338.00 CDN
Product Name: Anti-Human (CD45R), FITC (clone YTH 80.103), (Rat IgG2b)
Code:
CL7606F
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$364.00 CDN
Product Name: Anti-Human (CD45R), No Azide (Clone YTH 80.103), (Rat IgG2b)
Code:
CL7606NA
Supplier:
Cedarlane
Size:
1 mg
Unit Price:
$922.00 CDN
Product Name: Anti-Human (CD45R), PE (clone YTH 80.103), (Rat IgG2b)
Code:
CL7606PE
Supplier:
Cedarlane
Size:
50 ug
Unit Price:
$299.00 CDN

  • References

    1)  Dianzani U, Redoglia V, Malavasi F, et al. Isoform-specific associations of CD45 with accessory molecules in human T lymphocytes. Eur J Immunol. Feb; 22(2):365-71. 1992.

    2)  Hale G, Clark M, Waldmann H. Therapeutic potential of rat monoclonal antibodies: isotype specificity of antibody-dependent cell-mediated cytotoxicity with human lymphocytes. J Immunol. May; 134(5):3056-61. 1985.

Custom Antibody Services

CEDARLANE® manufactures complement, Lympholyte® cell separation media, cell purification immunocolumns, neuronal cell lines and a wide range of antibodies. CEDARLANE® continues to offer our Custom Antibody Services and increased demand has lead to the continued expansion of our facility. We understand the varied nature of custom work and encourage you to call our qualified staff to discuss the details of your project. Please inquire about other services not listed. Be assured that we at CEDARLANE® are dedicated to ensuring the confidentiality of all projects we discuss.



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