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Save 20% from Bethyl: Stated BEST recombinant monoclonal on the market for detection of HIF2-alpha in the IHC/ICC application

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Start Date:

Feb 9 2017

End Date:

Dec 31 2017

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Claimed the best recombinant monoclonal on the market for detection of HIF2-alpha in the IHC/ICC application!

Bethyl Laboratories is pleased to announce the addition of rabbit recombinant monoclonal antibodies, including HIF1-alpha and HIF2-alpha targets. All HIF1-alpha and HIF2-alpha antibodies are available as trial sizes. This expansion in the portfolio marks a milestone and will further support scientific discovery.

Antibodies against HIF2-alpha were assessed for specificity by immunocytochemistry (ICC). HIF2-alpha protein is rapidly degraded under normoxic conditions and stabilized under hypoxic conditions. Cobalt chloride treatment can be used as a mimetic agent for hypoxia to stimulate HIF2-alpha stabilization. Antibodies against HIF2-alpha were compared by staining HepG2 cells treated with cobalt chloride or mock-treated.

  • Host: Rabbit
  • Antibody Type: Recombinant Monoclonal
  • Conjugate: Unconjugated

Gene and Protein Information

  • Gene ID: 2034, 3091
  • Gene Name: endothelial PAS domain protein 1, hypoxia inducible factor 1 alpha subunit
  • Gene Symbol: EPAS1, HIF1A
  • Uniprot ID: Q16665, Q99814
  • Protein Name: Endothelial PAS domain-containing protein 1, Hypoxia-inducible factor 1-alpha
  • Alternate Names: ARNT interacting protein• ARNT-interacting protein• basic-helix-loop-helix-PAS protein MOP1• basic-helix-loop-helix-PAS protein MOP2• bHLHe73• bHLHe78• class E basic helix-loop-helix protein 73• class E basic helix-loop-helix protein 78• ECYT4• EPAS-1• HIF1• HIF-1 alpha-like factor• HIF-1A• HIF-1alpha• HIF-1-alpha• HIF1-ALPHA• HIF-1-alpha-like factor• HIF-1alpha-like factor• HIF2A• HIF-2-alpha• HIF2-alpha• HLF• hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)• hypoxia-inducible factor 1 alpha isoform I.3• hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)• hypoxia-inducible factor 2 alpha• hypoxia-inducible factor 2-alpha• hypoxia-inducible factor1alpha• member of PAS protein 1• member of PAS protein 2• member of PAS superfamily 1• MOP1• MOP2• PAS domain-containing protein 2• PAS domain-containing protein 8• PASD2• PASD8
Product Name Size Cat. #
HIF1-ALPHA HIF2-ALPHA ABVANTAGE TRIAL PACK 1 Pack (1 each of A700-001-T, A700-002-T and A700-003-T) A711-000-T

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Note: This offer is not valid in conjunction with contract discounts or any other special pricing. Void where prohibited. Discount does not apply to ALL Electron Microscopy Sciences products; some restrictions apply. Contact your Cedarlane Sales or Customer Service Representative for further details.