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CODING CELLS, THE BUILDING BLOCKS OF LIFE
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bit.bio is an award-winning human synthetic biology enterprise based in Cambridge, UK. Their mission is to code cells for health. To do so, we apply the principles of computation to biology.
Their current focus is to develop a scalable technology platform capable of producing consistent batches of every human cell. This has the potential to unlock a new generation of medicine: it will enable research and drug discovery to move on from inappropriate models and work with the cells that actually are affected by human disease. A scalable platform of consistent cells will also be the basis for a new generation of cell and tissue therapies.
Human induced pluripotent stem cells (iPSC)s have been reprogrammed using their breakthrough technology: opti-ox™¹ (optimized inducible over-expression). Human stem cells, within days, convert into consistent, mature, functional cell types providing a high quality human model.
Ready-to-culture cells are suitable as models for research in cell-type specific biology, target validation and drug screening in pharmaceutical R&D, and toxicology testing
Applications:
- Academic research
- Drug development
- Neurotoxicology
- High-throughput screening
- Genetic screening (e.g. CRISPR screening)
- 3D bioprinting
- Neuromuscular junctions
- Metabolism Research
Batch to batch reproducibility and homogeneity create a stable human model that is ready for experimentation as early as 2 days post revival.
Industrial scale quantities at a price point that allows the cells to be used from research to screening scale.
Cells arrive programmed to rapidly mature upon revival. Easy to use, only one medium required in a simple two-step protocol.
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