Mirus Bio - The Transfection Experts

Mirus Bio was founded on the principle that non-viral (i.e. plasmid DNA based) methods offer distinct performance advantages over viral methods of gene transfer.

Mirus Bio has played an important role in the history of the development of nucleic acid research reagents, distinguished by its many accomplishments:

• Developed and produced an siRNA transfection reagent, the first of its kind
• Pioneered development of high efficiency/low toxicity transfection formulations
• First to market single-step nucleic acid labeling technology applications
• Unique technology to label native, biologically relevant short RNA species, such as microRNA

In 2021, Mirus Bio continues to develop a wide range of non-viral delivery technologies, using proteins, polymers, and lipids in conjunction with novel chemistries that provide unique nucleic acid delivery capabilities.

Mirus Bio Research Products

TransIT® Transfection Reagents for high efficiency, low toxicity delivery of DNA, siRNA/miRNA and large RNA

• Mirus’ TransIT® Reagents are unique lipid and polymer formulations that achieve superior delivery efficiency of pDNA, siRNA/miRNA and large RNA with minimal cytotoxic effects. They have been optimized for In Vitro delivery in a variety of mammalian cells as well as for In Vivo delivery in small animals.
• The TransIT-PRO® Transfection Kit is specifically developed for DNA transfection of suspension 293 and CHO derived cells - ideal for biotherapeutic protein production. Accordingly, Mirus Bio offers a 1 mL sample size of TransIT-PRO® for qualified leads.
• Other notable products to join the Mirus Bio collection include TransIT®-Insect, TransIT®-BrCa and TransIT-X2®, all of which were launched in 2013.

Ingenio® Electroporation Kits and Solutions compatible with most electroporators, including the amaxa Nucleofector

• The Ingenio® Electroporation Solution allows researchers to deliver nucleic acids to cells that are resistant to transfection.

Label IT® Labeling Reagents for fluorescent and biotin labeling of all nucleic acids including miRNA

• The company’s Label IT® Kits employ proprietary chemistry to covalently attach labeling molecules to DNA and RNA. This simple one-step process is faster and more robust than traditional multi-step enzymatic labeling, and can be used for intracellular tracking, chromosome analysis, and microarray labeling.