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“The Transfection Experts”
Mirus was founded on the principle that non-viral (i.e. plasmid DNA based) methods offer distinct advantages over viral methods of gene transfer. Following this path, Mirus has pioneered the development of a wide range of non-viral delivery technologies using proteins, polymers, and lipids in conjunction with novel chemistries that provide unique nucleic acid delivery capabilities.
Mirus is a recognized leader in developing innovative nucleic acid research reagents, distinguished by its many accomplishments:
- First to develop an siRNA transfection reagent
- Pioneered development of high efficiency/low toxicity transfection formulations
- First to market a single step nucleic acid labeling technology
- Unique technology to label native, biologically relevant short RNA species such as microRNA
Mirus is well-known for its TransIT-PRO® product range. The TransIT-PRO® Transfection Kit is specifically developed for DNA transfection of suspension 293 and CHO derived cells - ideal for biotherapeutic protein production. Accordingly, Mirus Bio offers a 1 mL sample size of TransIT-PRO® for qualified leads.
New, notable products include TransIT®-Insect, TransIT®-BrCa and TransIT-X2®, all of which were launched in 2013.
Research Products include:
TransIT® Transfection Reagents for high efficiency, low toxicity delivery of DNA, siRNA/miRNA and large RNA
Ingenio® Electroporation Kits and Solutions compatible with most electroporators, including the amaxa Nucleofector
Label IT® Labeling Reagents for fluorescent and biotin labeling of all nucleic acids including miRNA
Mirus’ TransIT® Reagents are unique lipid and polymer formulations that achieve superior delivery efficiency of pDNA, siRNA/miRNA and large RNA with minimal cytotoxic effects. They have been optimized for In Vitro delivery in a variety of mammalian cells as well as for In Vivo delivery in small animals. The Ingenio® Electroporation Solution allows researchers to deliver nucleic acids to cells that are resistant to transfection.
The company’s Label IT® Kits employ proprietary chemistry to covalently attach labeling molecules to DNA and RNA. This simple one-step process is faster and more robust than traditional multi-step enzymatic labeling, and can be used for intracellular tracking, chromosome analysis, and microarray labeling.
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