Anti-Mouse CD8a (Ly 2) APC (Clone CT-CD8a) (rat IgG2a)
DescriptionCedarlane’s anti-mouse CD8a antigen monoclonal antibody binds to a protein of approximately 30,000 daltons found on 85% of mouse thymocytes, mouse cytotoxic/suppressor T cells and their precursors. It does not bind to mouse helper/inducer T cells. This antibody is not strain specific and can be used with all commonly used laboratory mice.
This antibody is suitable for use in flow cytometry, in vivo assays and immunohistochemistry (Frozen and paraffin-embedded sections).______________________________________________________________________________________________________Flow Cytometry AnalysisC57BL/6 mouse splenic T-cells (left) or thymocytes (right) were stained with anti-CD8a (clone: CT-CD8a) (filled histogram) or rat IgG2a isotype control (open histogram).
1) Tomonari, K. and Spencer, S. (1990) Epitope-specific binding of CD8 regulates activation of T cells and induction of cytotoxicity. International Immunolgy 2(12):1189-1194.