Mouse Suprachiasmatic Nucleus
This product is based on a proprietary platform technology which has enabled the creation of a series of immortalized hypothalamic neurons. Primary neurons were micro dissected from the suprachiasmatic nucleus (SCN) area of the hypothalamus from 6 adult female C57Bl/6 mice. Pooled primary cultures were immortalized by retroviral transfer of the SV40 T-Ag. No further sub-cloning of the immortalized cells was done.
This cell line has been found to express an ever expanding array of neuropeptides, enzymatic markers and biologically active receptors. As such, this cell line will enable accurate in-vitro assays for use in the discovery, development and validation of new therapeutics targeted to central-nervous system diseases and disorders, including obesity, stress, and metabolic disorders, amongst others.
The datasheet for this product can be downloaded here.
CEDARLANE® manufactures complement, Lympholyte® cell separation media, cell purification immunocolumns, neuronal cell lines and a wide range of antibodies. CEDARLANE® continues to offer our Custom Antibody Services and increased demand has lead to the continued expansion of our facility. We understand the varied nature of custom work and encourage you to call our qualified staff to discuss the details of your project. Please inquire about other services not listed. Be assured that we at CEDARLANE® are dedicated to ensuring the confidentiality of all projects we discuss.