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Cedarlane › Reagents › Cedarlane Manufactured › Reagents For Human › CD Antibodies › CD21 (CR2) › 21A/5

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Custom Antisera

CEDARLANE® manufactures Complement, Lympholyte® cell separation media, cell purification Immunocolumns and a wide range of Antibodies. Also, CEDARLANE® continues to offer our Custom Antibody Services.

  

Cedarlane-manufactured Reagents

Our line of Cedarlane-manufactured reagents.

21A/5

  • Description

    Cedarlane’s anti-Human CD21 monoclonal antibody specifically binds human CD21, also known as Complement component (3d/Epstein Barr virus) receptor 2 (CR2).  CD21 is a protein expressed on mature B cells and follicular dendritic cells, and is weakly expressed on immature thymocytes and T lymphocytes.  CD21 binds to C3d, C3dg, and iC3b in the complement system.  Other ligands include Epstein Barr virus and Interferon alpha.  CD21 plays a role in B cell activation by binding to CD23 and forming a co-receptor complex with CD19, CD81, and Leu13.
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    Flow Cytometry Analysis
    Human peripheral blood lymphocytes were stained with anti-CD21 (clone: 21A/5) (filled histogram) or Mouse IgG1 isotype control (open histogram).
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    Immunofluorescence Analysis

    Purified Anti-Human CD21 (CL7613AP) staining of paraformaldehyde-fixed paraffin-embedded human tonsil sections at 200x (A) and 400x (B) magnification with DAPI counterstain. (Mouse anti-human CD21 mAb (CL7613AP) 1:500; Alexa Fluor 488 Goat anti-mouse 1:500 (Molecular Probes) and Normal Goat Serum (blocking)) 
       
Product Name: Anti-Human CD21/CR2 (Complement Receptor 2), Alexa Fluor488 (clone:21A/5) (Mouse IgG1)
Code:
CL7613AF4
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$475.00 CDN
Product Name: Anti-Human CD21/CR2 (Complement Receptor 2), Alexa Fluor647 (clone:21A/5) (Mouse IgG1)
Code:
CL7613AF6
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$475.00 CDN
Product Name: Anti-Human CD21/CR2 (Complement Receptor 2), Purified (clone:21A/5) (Mouse IgG1)
Code:
CL7613AP
Supplier:
Cedarlane
Size:
200 ug
Unit Price:
$496.00 CDN
Product Name: Anti-Human CD21/CR2 (Complement Receptor 2), APC (clone:21A/5) (Mouse IgG1)
Code:
CL7613APC
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$570.00 CDN
Product Name: Anti-Human CD21/CR2 (Complement Receptor 2), Biotin (clone:21A/5) (Mouse IgG1)
Code:
CL7613B
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$338.00 CDN
Product Name: Anti-Human CD21/CR2 (Complement Receptor 2), FITC (clone:21A/5) (Mouse IgG1)
Code:
CL7613F
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$364.00 CDN
Product Name: Anti-Human CD21/CR2 (Complement Receptor 2), PE (clone:21A/5) (Mouse IgG1)
Code:
CL7613PE
Supplier:
Cedarlane
Size:
50 ug
Unit Price:
$299.00 CDN

  • References

    1)  CD Guide for CD21 (1989) In Knapp W, et al (eds) Leucocyte Typing IV, Oxford University Press, Oxford, New York and Tokyo, p 1080. ISBN-13: 978-0192618672


    2)  Kovacs JM, Hannan JP, Eisenmesser EZ, Holers VM. (2009) Mapping of the C3d ligand binding site on complement receptor 2 (CR2/CD21) using nuclear magnetic resonance and chemical shift analysis. J Biol Chem. 284 (14):9513-20.

Custom Antibody Services

CEDARLANE® manufactures complement, Lympholyte® cell separation media, cell purification immunocolumns, neuronal cell lines and a wide range of antibodies. CEDARLANE® continues to offer our Custom Antibody Services and increased demand has lead to the continued expansion of our facility. We understand the varied nature of custom work and encourage you to call our qualified staff to discuss the details of your project. Please inquire about other services not listed. Be assured that we at CEDARLANE® are dedicated to ensuring the confidentiality of all projects we discuss.



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