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Custom Antisera
CEDARLANE® manufactures Complement, Lympholyte® cell separation media, cell purification Immunocolumns and a wide range of Antibodies. Also, CEDARLANE® continues to offer our Custom Antibody Services.
Cedarlane-manufactured Reagents
Our line of Cedarlane-manufactured reagents.
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PK136
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DescriptionCedarlane’s anti-mouse NK cells monoclonal antibody is specific for mouse NK cells in selected strains of mice (i.e.C57BL, FVB/N, NZB but not A, AKR, BALB/c, CBA/J, C3H, C57BR, C58, DBA/1, DBA/2, SJL and 129). Clone PK136 is specific for mouse NK1.1, also known as NKR-PIC and Ly 55. Mouse NK1.1 is expressed on NK cells and NKT cells on the following strains: C57BL, FVB/N and NZB. There are published reports that PK136 mAb binds to NKR-PIB on SJL/K NK cells4.This antibody is suitable for use in flow cytometry and with paraffin-embedded sections.______________________________________________________________________________________________________Immunohistochemical Analysis
Biotin Anti-Mouse NK Cells (NK1.1) (CL8994B) staining of paraformaldehyde-fixed paraffin-embedded mouse spleen sections at 2.5x (Left) and 40x (Right) magnification. (Biotin Anti-mouse NK Cells (NK1.1) (CL8994B) was used at a dilution of 1:100 and stained with DAB for 1 minute)
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| Product Name:
Anti-Mouse NK Cells (NK1.1), Alexa Fluor®488 (Clone PK136) (mouse IgG2a)
Code:
CL8994AF4
Supplier:
Cedarlane
Size:
100 ug
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Anti-Mouse NK Cells (NK1.1), Alexa Fluor®647 (Clone PK136) (mouse IgG2a)
Code:
CL8994AF6
Supplier:
Cedarlane
Size:
100 ug
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Anti-Mouse NK Cells (NK1.1), Alexa Fluor®700 (Clone PK136) (mouse IgG2a)
Code:
CL8994AF7
Supplier:
Cedarlane
Size:
100 ug
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Anti-Mouse NK Cells (NK1.1), Purified (Clone PK136) (mouse IgG2a)
Code:
CL8994AP
Supplier:
Cedarlane
Size:
250ug
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| Product Name:
Anti-Mouse NK Cells (NK1.1), APC (Clone PK136) (mouse IgG2a)
Code:
CL8994APC
Supplier:
Cedarlane
Size:
0.1 mg
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| Product Name:
Anti-Mouse NK Cells (NK1.1), Biotin (Clone PK136) (mouse IgG2a)
Code:
CL8994B
Supplier:
Cedarlane
Size:
100ug
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| Product Name:
Anti-Mouse NK Cells (NK1.1), Biotin (Clone PK136) (mouse IgG2a)
Code:
CL8994B-3
Supplier:
Cedarlane
Size:
300ug
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| Product Name:
Anti-Mouse NK Cells (NK1.1), FITC (Clone PK136) (mouse IgG2a)
Code:
CL8994F
Supplier:
Cedarlane
Size:
100ug
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| Product Name:
Anti-Mouse NK Cells (NK1.1), Purified, Low Endotoxin (Clone PK136) (mouse IgG2a)
Code:
CL8994LE
Supplier:
Cedarlane
Size:
500 ug
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| Product Name:
Anti-Mouse NK Cells (NK1.1), No Azide (Clone PK136) (mouse IgG2a)
Code:
CL8994NA
Supplier:
Cedarlane
Size:
1mg
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References
1) Koo, G.C. and Peppard, J.R. 1981. Establishment of monoclonal anti-NK-1.1 antibody, Hybridoma 3:301-303.
2) Koo, G.C., Dumont, F., Hackett, J.Jr,]., Tutt, M. and Kumar, V. 1986. The NK-1/1(-) mouse: A model to study differentiation of murine NK cells. J. Immunol. 137:3742-3737.
3) Kung, S.K.P., and Miller, R.G. 1985. The NK1.1 antigen in NK-mediated F1 antiparent killing in vitro. J. Immunol. 154:1624.
4) Kung, S.K.P., Ruey-Chyi, S., Shannon, J. and R. Miller. 1999. The NKR-P1B Gene product is an inhibitory receptor on SJL/J NK cells. J. Immunol. 162 (10) 5876.
5) Wang, M., et al, 1998. Natural Killer Cell Depletion Fails to Influence Initial CD4 T Cell Commitment In Vivo in Exogenous Antigen-Stimulated Cytokine and Antibody Responses. J. Immunol 160: 1098-1105.
6) Zhao, Y., Sergio, J., Swenson, K., Arn, J., et al, 1997. Positive and Negative Selection of Functionala Mouse CD4 Cells by Porcine MHC in Pig Thymus Grafts. 159: 2100-2107.
7) Williams, N.S., and Engelhard, V. 1997. Perforin-Dependent Cytotoxic Activity and Lymphokine Secretion by CD4+ T cells are Regulated by CD8+ T cells. J. Immunology 159: 2091-2099.
Custom Antibody Services
CEDARLANE® manufactures complement, Lympholyte® cell separation media, cell purification immunocolumns, neuronal cell lines and a wide range of antibodies. CEDARLANE® continues to offer our Custom Antibody Services and increased demand has lead to the continued expansion of our facility. We understand the varied nature of custom work and encourage you to call our qualified staff to discuss the details of your project. Please inquire about other services not listed. Be assured that we at CEDARLANE® are dedicated to ensuring the confidentiality of all projects we discuss.

