+1 800 268-5058
Register | Login
Store:

Quick Add



Reagents Quick Links

Custom Antisera

CEDARLANE® manufactures Complement, Lympholyte® cell separation media, cell purification Immunocolumns and a wide range of Antibodies. Also, CEDARLANE® continues to offer our Custom Antibody Services.

  

Prolactin Receptor

  • Description

    Prolactin (PRL) is a pituitary hormone involved in a variety of essential functions including reproduction, ion transport, growth, development and immunoregulation. It is also classified as a cytokine and influences different cell types through a signal transduction pathway upon ligand binding and dimerization of the Prolactin Receptor. The transmembrane PRL receptor, a member of the cytokine receptor superfamily, can be found in long and short forms depending on tissue source and species (ranging from ~40 kDa to 100 kDa). Signal transduction is mediated with the aid of members of the JAK/STAT signaling pathway.
    ______________________________________________________________________________________________________

    Immunofluorescence Analysis


    Purified Anti-Rat/Mouse Prolactin Receptor (CL093AP) staining of paraformaldehyde-fixed paraffin-embedded rat pituitary sections at 400x magnification. (Rabbit anti-rat/mouse Prolactin Receptor (CL093AP) 1:500; Alexa Fluor 488 Goat anti-rabbit 1:500 (Molecular Probes) and Normal Goat Serum (blocking))
       
Product Name: Anti-Rat/Mouse Prolactin Receptor, Purified, (polyclonal), (Rabbit IgG)
Code:
CL093AP
Supplier:
Cedarlane
Size:
100ug
Unit Price:
$388.00 CDN
Product Name: Anti-Rat/Mouse Prolactin Receptor, Purified, (polyclonal), (Rabbit IgG)
Code:
CL093AP-S
Supplier:
Cedarlane
Size:
25ug
Unit Price:
$136.00 CDN
  • References

    1)  Swaminathan G, Varghese B, and Fuchs SY  (2008). Regulation of prolactin receptor levels and activity in breast cancer. J Mammary Gland Biol Neoplasia. 13(1): 81-91.

    2)  Devi YS, Shehu A, Halperin J, Stocco C, Le J, Seibold AM and Gibori G (2009). Prolactin signalling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive tissues.Reproductive Biology and Endocrinology. 7:87.

Custom Antibody Services

CEDARLANE® manufactures complement, Lympholyte® cell separation media, cell purification immunocolumns, neuronal cell lines and a wide range of antibodies. CEDARLANE® continues to offer our Custom Antibody Services and increased demand has lead to the continued expansion of our facility. We understand the varied nature of custom work and encourage you to call our qualified staff to discuss the details of your project. Please inquire about other services not listed. Be assured that we at CEDARLANE® are dedicated to ensuring the confidentiality of all projects we discuss.



Cleardot