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Cedarlane › Reagents › Cedarlane Manufactured › Reagents For Mouse › Miscellaneous Antibodies › Complement Component C3 › RmC11H9

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Custom Antisera

CEDARLANE® manufactures Complement, Lympholyte® cell separation media, cell purification Immunocolumns and a wide range of Antibodies. Also, CEDARLANE® continues to offer our Custom Antibody Services.

  

Cedarlane-manufactured Reagents

Our line of Cedarlane-manufactured reagents.

RmC11H9

  • Description

    Cedarlane’s Anti-Mouse Complement Component C3 monoclonal antibody reacts with mouse C3 as well as the breakdown products C3b, iC3b and C3dg. C3 is the most abundant complement protein in serum.  C3 and its cleavage products, C3a and C3b, play a central role in the complement activation cascade.  C3b forms an integral part of the C3 and C5 convertases as it promotes complement activation and the subsequent formation of the membrane attack complex. C3a possesses anaphylatoxic as well as various immunoregulatory properties.

    Also, C3 has been implicated in developmental and non-imflammatory process such as hematopoiesis, skeletal and vascular development and reproduction.

    Reported applications of this antibody include immunofluorescence2, 5, ELISA4, Western blots1, flow cytometry and immunohistochemistry1, 3 on acetone fixed frozen sections.
    ______________________________________________________________________________________________________

    Flow Cytometry Analysis
    C3H/He mouse thymocytes incubated with anti-mouse CD90 (Thy 1.2) (clone: 5a-8) and fresh mouse serum were stained with anti-mouse C3 (clone: RmC11H9) (filled histogram) or rat IgG2a isotype control (open histogram).
       
Product Name: Anti-Mouse Complement Component C3, Alexa Fluor®488 (Clone RmC11H9) (rat IgG2a)
Code:
CL7503AF4
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$482.00 CDN
Product Name: Anti-Mouse Complement Component C3, Purified (Clone RmC11H9) (rat IgG2a)
Code:
CL7503AP
Supplier:
Cedarlane
Size:
250ug
Unit Price:
$503.00 CDN
Product Name: Anti-Mouse Complement Component C3, Purified (Clone RmC11H9) (rat IgG2a)
Code:
CL7503AP-2
Supplier:
Cedarlane
Size:
500ug
Unit Price:
$765.00 CDN
Product Name: Anti-Mouse Complement Component C3, APC (Clone RmC11H9) (rat IgG2a)
Code:
CL7503APC
Supplier:
Cedarlane
Size:
100 ug
Unit Price:
$559.00 CDN
Product Name: Anti-Mouse Complement Component C3, Biotin (Clone RmC11H9) (rat IgG2a)
Code:
CL7503B
Supplier:
Cedarlane
Size:
100ug
Unit Price:
$292.00 CDN
Product Name: Anti-Mouse Complement Component C3, FITC (Clone RmC11H9) (rat IgG2a)
Code:
CL7503F
Supplier:
Cedarlane
Size:
100ug
Unit Price:
$329.00 CDN
Product Name: Anti-Mouse Complement Component C3, No Azide (Clone RmC11H9) (rat IgG2a)
Code:
CL7503NA
Supplier:
Cedarlane
Size:
1mg
Unit Price:
$1312.00 CDN
Product Name: Anti-Mouse Complement Component C3, PE (Clone RmC11H9) (rat IgG2a)
Code:
CL7503PE
Supplier:
Cedarlane
Size:
50ug
Unit Price:
$309.00 CDN
Product Name: Anti-Mouse Complement Component C3, TRITC, (Clone RmC11H9) (rat IgG2a)
Code:
CL7503TRC
Supplier:
Cedarlane
Size:
100ug
Unit Price:
$365.00 CDN

  • References

    1)  Kremmer, E et al. (1990). Hybridoma. 9 (4):309-17.

    2)  Robson, M et al. (2001). J. Immunol. 166(11): 6820-6828.

    3)  Mastellos et al. (2004).  Molecular Immunology 40: 1213-1221.

    4)  Zhili Xu et al. (2008). J. Virology. 82(23): 11705-13.

    5)  Binstadt, B et al. (2009). PNAS. 106(39): 16758-63.

Custom Antibody Services

CEDARLANE® manufactures complement, Lympholyte® cell separation media, cell purification immunocolumns, neuronal cell lines and a wide range of antibodies. CEDARLANE® continues to offer our Custom Antibody Services and increased demand has lead to the continued expansion of our facility. We understand the varied nature of custom work and encourage you to call our qualified staff to discuss the details of your project. Please inquire about other services not listed. Be assured that we at CEDARLANE® are dedicated to ensuring the confidentiality of all projects we discuss.



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