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Embryonic Mouse Hypothalamus Cell Line N4 (mHypoE-N4)
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Product Code:
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CLU103 |
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Supplier Name:
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Cellutions Biosystems Inc. |
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Size:
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1 mL |
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Extra Notes:
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Please inquire for pricing.MTA required. |
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Categories:
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Embryonic Mouse Hypothalamic |
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Embryonic Mouse Hypothalamic Cell Lines
This product line is based on a proprietary platform technology which has enabled the creation of a series of immortalized hypothalamic neurons; immortalized from mouse embryonic day 15, 17, 18 hypothalamic primary cultures by retroviral transfer of SV40 T-Ag. These cell lines have been found to express an ever expanding array of neuropeptides, enzymatic markers and biologically active receptors.
As such, these cell lines enable accurate in-vitro assays for use in the discovery, development and validation of new therapeutics targeted to central-nervous system diseases and disorders, including obesity, stress, and metabolic disorders, amongst others.
Peptides
- Neuropeptide Y (NPY)
- Pro-opiomelanocortin (POMC)
- Corticotropin Releasing Hormone (CRF)
- Galanin
- Agouti-related Peptide (AgRP)
- Proglucagon
- Growth Hormone Releasing Hormone (GHRH)
- Urocortin
- Orexin
- Melanocortin-concentrating Hormone (MCH)
- Oxytocin
- Ghrelin
- Neurotensin (NT)
- Arginine vasopressin
Receptors
- Estrogen Receptor alpha
- Estrogen Receptor beta
- Androgen Receptor (AR)
- Glucagon-like Peptide 1 (Glp1-R)
- Glucagon-like Peptide 2 (Glp2-R)
- Leptin
- Growth Hormone Secretagogue (GHS-R/Ghrelin-R)
- Neurotensin (NTR-1)
- Melanocortin (MC4R)
- Progesterone (PR)
- Insulin R
- Melanin-concentrating Hormone (MCH R1)
- Neuropeptide Y 1,2,4,5 (NPY)
- Adiponectin R1 & R2
Enzymes
- Tyrosine hydroxylase
- Tryptophan hydroxylase
- Aromatase
- Glucokinase
- Choline acetyltransferase
- Glutamic acid decarboxylase (GAD 67)
For information regarding additional markers not listed or to find out how these cell lines can easily be screened for additional peptides, receptors, and markers of interest, please contact us for more details.
For detailed information regarding cell line expression please click the Catalogue # highlighted in the table below:
