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Custom Antisera
CEDARLANE® manufactures Complement, Lympholyte® cell separation media, cell purification Immunocolumns and a wide range of Antibodies. Also, CEDARLANE® continues to offer our Custom Antibody Services.
Cedarlane-manufactured Reagents
Our line of Cedarlane-manufactured reagents.
- Animal Red Blood Cell Reagents
- Complement Antibodies & Proteins
- Complement Reagents
- Haemostasis Reagents
- Lympholyte® Cell Separation Media for the isolation of PBMCs and PMNs
- Neuroscience Reagents
- Reagents For Human
- Reagents For Mouse
- Reagents For Rat
- Secondary Reagents
- Specialty Products
- Tools for Flow Cytometry
OX-42
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DescriptionCedarlane’s anti-rat CD11b/c monoclonal antibody recognizes most macrophages including resident peritoneal macrophages, kupffer cells, but only approximately 35% of alveolar macrophages (2). It also labels dendritic cells extensively, granulocytes and cells with morphology of microglia in the brain. It precipitates three polypeptides of M.W. 160, 103 and 95kDa. OX-42 inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor for iC3b called CR3. Cedarlane’s anti-rat CD11b/c mAb should prove useful in the recognition of macrophages and microglia.
This clone is reported to work with frozen and paraffin sections (3); in vivo and in vitro functional tests (4, 5, 6); and cryostat sections (5).______________________________________________________________________________________________________Flow Cytometry AnalysisWistar rat peritoneal macrophages were stained with anti-CD11b/c (clone: OX-42) (filled histogram) or mouse IgG2a isotype control (open histogram).
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Product Name:
Anti-Rat CD11b/c Ascites (Clone OX-42) (mouse IgG2a)
Code:
CL042A
Supplier:
Cedarlane
Size:
0.5ml
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Product Name:
Anti-Rat CD11b/c Alexa Fluor®488 (Clone OX-42) (mouse IgG2a)
Code:
CL042AF4
Supplier:
Cedarlane
Size:
100 ug
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Product Name:
Anti-Rat CD11b/c Alexa Fluor®647 (Clone OX-42) (mouse IgG2a)
Code:
CL042AF6
Supplier:
Cedarlane
Size:
100 ug
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Product Name:
Anti-Rat CD11b/c Alexa Fluor®700 (Clone OX-42) (mouse IgG2a)
Code:
CL042AF7
Supplier:
Cedarlane
Size:
100 ug
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Product Name:
Anti-Rat CD11b/c Purified (Clone OX-42) (mouse IgG2a)
Code:
CL042AP
Supplier:
Cedarlane
Size:
250ug
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Product Name:
Anti-Rat CD11b/c Purified (Clone OX-42) (mouse IgG2a)
Code:
CL042AP-2
Supplier:
Cedarlane
Size:
500ug
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Product Name:
Anti-Rat CD11b/c APC (Clone OX-42) (mouse IgG2a)
Code:
CL042APC
Supplier:
Cedarlane
Size:
100ug
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Product Name:
Anti-Rat CD11b/c Biotin (Clone OX-42) (mouse IgG2a)
Code:
CL042B
Supplier:
Cedarlane
Size:
100ug
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Product Name:
Anti-Rat CD11b/c Biotin (Clone OX-42) (mouse IgG2a)
Code:
CL042B-5
Supplier:
Cedarlane
Size:
500ug
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Product Name:
Anti-Rat CD11b/c FITC (Clone OX-42) (mouse IgG2a)
Code:
CL042F
Supplier:
Cedarlane
Size:
100ug
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References
1) Aihara, N. et al. (1995) J. Neurotrauma. 12:53-63.
2) Robinson, A.P. et al. (1986) Immunology. 57:239-247.
3) Whiteland J.L. et al. (1995) J. Histochem and Cytochem. 43:313-320.
4) Issekutz, A. C. and T.B. Issekutz, (1992) Immunology. 76:655-661.
5) Yamazaki, T. et al. (1993) Am. J. of Pathology. 143:410-418.
6) Tamatani, T. et al. (1991) Eur. J. Immunol. 21:627-633.
7) Joan Y. et al. (2009) Am J Physiol Regul Integr Comp Physiol. 297:R1532-R1545.
8) Zheng Gen Piao et al. (2005) Pain. 121:219-231.
9) Abbadie C. et al. (2003) PNAS. 100:7947-7952.10) Lee. et al. (2010) Molecular Pain. 6:79.11) Summy-Long, J.Y. et al. (2008) Journal of Neuroendocrinology. 20:1224-1232.
Custom Antibody Services
CEDARLANE® manufactures complement, Lympholyte® cell separation media, cell purification immunocolumns, neuronal cell lines and a wide range of antibodies. CEDARLANE® continues to offer our Custom Antibody Services and increased demand has lead to the continued expansion of our facility. We understand the varied nature of custom work and encourage you to call our qualified staff to discuss the details of your project. Please inquire about other services not listed. Be assured that we at CEDARLANE® are dedicated to ensuring the confidentiality of all projects we discuss.