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  • Lena Biosciences is a biotechnology company that develops, markets, and sells cutting-edge tools and services enabling the use of human cells in culture in a physiologically relevant setting. Their proprietary multi-well plate perfusion system, PerfusionPal™, mimics interstitial delivery of nutrients and drugs to organoids, 3D cell cultures, and tissue explants for translatable results.  PerfusionPal™ also provides superior oxygenation to enhance cell function and viability. Extending cell survival from days to weeks, even for primary cells, PerfusionPal™ is the only system capable of continuous perfusion of 12 statistically independent organ tissue/cell models in their own media with a single tube and a single pump. Lena Biosciences also offers a cell culture scaffold, SeedEZ, that allows the growth of cells in three dimensions (3D) as in living tissues. SeedEZ enables cells to utilize both their cadherin (cell-cell) and integrin (cell-ECM) receptors that are vital for tissue-representative cell behavior, drug responses, and cell therapy outcomes. Lastly, their Blood Substitute product carries and releases air, mimicking the function of hemoglobin for oxygen delivery. This enables superior interstitial delivery of all gases to cells that are cultured in PerfusionPal, thus increasing cellular respiratory metabolism several fold, and drug metabolism by at least an order of magnitude compared to cells in a dish."

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