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TriLink BioTechnologies

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TriLink BioTechnologies Products

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  • TriLink BioTechnologies, part of Maravai LifeSciences, is a best-in-class contract development and manufacturing organization (CDMO) for synthesis of nucleic acids, NTPs and mRNA capping analogs. TriLink has scale-up expertise and unique production capabilities of mRNA, oligonucleotide & plasmid for companies focused on therapeutic, vaccine, diagnostic and biopharmaceutical breakthroughs. TriLink’s proprietary CleanCap® mRNA co-transcriptional capping technology simplifies mRNA manufacturing by removing additional enzymatic steps, resulting in high capping efficiency and improved yields over traditional co-transcriptional capping methods.

    TriLink’s CDMO services offer a range of manufacturing grade products from discovery-grade (RUO) to its customizable intermediate-grade - GMPLink™ to full GMP-grade with scale-up and technology transfer expertise. TriLink operates a quality system in compliance with ICH Q7, Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients, Section 19, APIs for Use in Clinical Trials, and ISO 9001:2015 standards.

    TriLink continues to expand its cGMP and general mRNA, oligonucleotide & plasmid manufacturing capacity at its new global headquarters to support therapeutic, vaccine and diagnostic customers.

    Specialty Oligonucleotides and Nucleoside Triphosphates

    TriLink offers:
    - Milligram to multigram capacity
    - Affordable, no-obligation oligo production following the FDA’s Quality System Regulations (QSR)
    - Industry-leading expertise and technical support
    - World-class proficiency in making highly- modified oligonucleotides
    - Oligonucleotide radiolabeling services

  • Streamlined mRNA Synthesis for Increased Protein Expression

    Join us as we review the design, manufacturing, and future technology options for synthesizing RNA for therapeutic purposes. We will further show proof-of-concept data using best-in-class streamlined mRNA manufacturing process to demonstrate benefits beyond turnaround time for a drug substance. If you'd like to access the recorded version featuring Jordana Henderson, Associate Director R&D at TriLink BioTechnologies, click the video below.

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