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Cedarlane › Reagents › Cedarlane Manufactured › Reagents For Mouse › TCR Antibodies › GL3

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GL3

  • Description

    Cedarlane's anti-mouse gdT cell receptor monoclonal antibody reacts with the surface on all gdTCR bearing cells and does not react with receptors on ab TCR positive cells. It is thought that this clone may be specific for a determinant present on Cd 7. The gd T cell receptors are present on murine CD4-CD8- thymocytes, peripheral T cells, intestinal CD8+ intraepithelial lymphocytes and Thy 1+ dendritic epidermal cells in the skin 1.

    Use of this antibody in conjunction with an anti-CD3 monoclonal antibody (Cedarlane's anti-CD3e Monoclonal Antibody CL7202, clone 145-2C11) allows for accurate measurements of the mutually exclusive sub-populations of gd TCR and abTCR bearing T cells. Cedarlane's anti mouse gd TCR monoclonal antibody has also been used successfully for the characterization of murine intraepithelial lymphocytes.

    This clone is reported to work with frozen sections6.
    ______________________________________________________________________________________________________

    Flow Cytometry Analysis
    C3H/He mouse splenic T-cells were stained with anti-gamma/delta TCR (clone: GL3) (filled histogram) or Armenian hamster IgG isotype control (open histogram).
       
Product Name: Anti-Mouse gamma/delta TCR, Ascites (Clone GL3) (hamster IgG)
Code:
CL7201A
Supplier:
Cedarlane
Size:
0.5ml
Unit Price:
$616.00 CDN
Product Name: Anti-Mouse gamma/delta TCR, Purified (Clone GL3) (hamster IgG)
Code:
CL7201AP
Supplier:
Cedarlane
Size:
250ug
Unit Price:
$309.00 CDN
Product Name: Anti-Mouse gamma/delta TCR, Biotin (Clone GL3) (hamster IgG)
Code:
CL7201B
Supplier:
Cedarlane
Size:
100ug
Unit Price:
$181.00 CDN
Product Name: Anti-Mouse gamma/delta TCR, Biotin (Clone GL3) (hamster IgG)
Code:
CL7201B-3
Supplier:
Cedarlane
Size:
300ug
Unit Price:
$501.00 CDN
Product Name: Anti-Mouse gamma/delta TCR, FITC (Clone GL3) (hamster IgG)
Code:
CL7201F
Supplier:
Cedarlane
Size:
100ug
Unit Price:
$201.00 CDN
Product Name: Anti-Mouse gamma/delta TCR, FITC (Clone GL3) (hamster IgG)
Code:
CL7201F-3
Supplier:
Cedarlane
Size:
300ug
Unit Price:
$473.00 CDN
Product Name: Anti-Mouse gamma/delta TCR, No Azide (Clone GL3) (hamster IgG)
Code:
CL7201NA
Supplier:
Cedarlane
Size:
1mg
Unit Price:
$805.00 CDN
Product Name: Anti-Mouse gamma/delta TCR, PE (Clone GL3) (hamster IgG)
Code:
CL7201PE
Supplier:
Cedarlane
Size:
50ug
Unit Price:
$193.00 CDN
Product Name: Anti-Mouse gamma/delta TCR, PE (Clone GL3) (hamster IgG)
Code:
CL7201PE-3
Supplier:
Cedarlane
Size:
300ug
Unit Price:
$749.00 CDN
Product Name: Anti-Mouse gamma/delta TCR, PE-Cy5 (Clone GL3) (hamster IgG)
Code:
CL7201TC
Supplier:
Cedarlane
Size:
100ug
Extra Notes:
PE-Cy5 conjugate currently unavailable. See other conjugates in CL7201 series for alternates.
Unit Price:
$503.00 CDN

  • References

    1)  Sunderland,C.A., McMaster, W.R., and A.F. Williams. (1979)  Eur. J.Immunol. 9, 155-159. Purification with monoclonal antibody of a predominant leukocyte-common antigen and glycoprotein from rat thymocytes.

    2)  Brown,W.R.A., Barclay,A.N., Sunderland,C.A. and A.F. Williams. (1981) Nature. 289, 1164-1177. Identification of a glycoprotein-like molecule at the cell surface of rat thymocytes.

    3)  Standring,R. and A.F. Williams. (1978) Biochim.Biophys. Acta. 508, 85-96. Glycoproteins and antigens of membranes prepared from rat thymocytes after lysis by shearing or with the detergent Tween-40.

    4)  Brown,W.R.A. and A.F. Williams. (1982) Immunology. 46, 713-726. Lymphocyte cell surface glycoproteins which bind to soybean and peanut lectins.

    5)  Woollet,G.R., Barclay,A.N., Puklavec,M. and A.F. Williams. (1985) Eur. J. Immunol. 15, 168-173. Molecular and antigenic heterogeneity of the rat leukocyte-common antigen from thymocytes and T and B lymphocytes.


    6)  Brouard, S., et al. (1999)  J. of Immunol. 162, 3367-3377. T Cell repertoire alterations of vascularized xenografts.

Custom Antibody Services

CEDARLANE® manufactures complement, Lympholyte® cell separation media, cell purification immunocolumns, neuronal cell lines and a wide range of antibodies. CEDARLANE® continues to offer our Custom Antibody Services and increased demand has lead to the continued expansion of our facility. We understand the varied nature of custom work and encourage you to call our qualified staff to discuss the details of your project. Please inquire about other services not listed. Be assured that we at CEDARLANE® are dedicated to ensuring the confidentiality of all projects we discuss.



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