Introducing MicroQuant™ by ATCC: Precision in Microbial Quality Control

Streamline your microbial QC testing with ATCC’s latest innovation, MicroQuant™. Specifically designed for pharmaceutical manufacturing, MicroQuant™ provides accurately quantitated microbial reference materials to ensure reliable, consistent, and precise results every time.

Why Choose MicroQuant™?:

Using cutting-edge cryopreservation technology, MicroQuant™ offers stable, single-use pellets that rehydrate rapidly, delivering fast, accurate, and reproducible results. Simplify your workflow and reduce turnaround times without compromising on quality.

Key Benefits:

• Precision Quantitation: Available in high (10^7-10^8 CFU) and low (100-1,000 CFU) titer formats, guaranteeing consistency across lots.
• Stringent quality control measures to uphold biopharmaceutical production standards.
• Single-Use Convenience: Ready-to-use pellets reduce setup time and eliminate the need for extensive microbial culture preparation.
• Single-Use Convenience: Ready-to-use pellets reduce setup time and eliminate the need for extensive microbial culture preparation.
• Easy Storage: Stable for up to 6 months at 2-8°C, ensuring availability when you need it.
• Trusted Quality: Manufactured under ISO 17034 by ATCC, ensuring top-tier quality and traceable source materials.

Stay ahead in microbial quality control—choose MicroQuant™ for dependable, efficient, and high-quality results.

Explore The MicroQuant™ Portfolio .

Cutting-Edge ThawReady™ Cells Now Available

Cell-based assays have lengthy timelines due to the requirement of cell expansion processes to get a synchronized cell stock. To speed up your timelines and provide the consistency you need, ATCC developed ThawReady™ Cells..

• Eliminate lengthy cell expansion - saving cost, time, and lab space
• Stringent quality control measures to uphold biopharmaceutical production standards.
• Ready within hours of thawing
• Single-Use Convenience: Ready-to-use pellets reduce setup time and eliminate the need for extensive microbial culture preparation.
• Scalable for high throughput assays

ATCC ThawReady™ cells streamline workflows by months, allowing you to focus on advancing drug discovery and development.

Explore our growing collection of Immuno-oncology cell lines – essential tools for cancer therapy research to alleviate human suffering.

Discover more at: www.atcc.org/thawready

Explore ThawReady™ (Assay Ready) Cells.

Unlock Innovation with ATCC’s Trusted and Diverse Cell Models

ATCC offers the world's largest and most diverse collection of authenticated human and animal cell lines, encompassing over 4,000 continuous cell lines categorized by species, tissue or disease types, and signaling pathways.

Key Offerings:

• Human Cells: ATCC provides a vast array of human cell cultures essential for scientific discovery and innovation.
• Animal Cells: The collection includes cell lines from more than 150 different species, serving as vital models for human disease research
• Primary Cells: Normal human primary cells that retain in vivo physiologies, with custom lots available from a diverse donor pool.
• Immortalized Primary Cells: hTERT-immortalized primary cells exhibiting normal in vivo biologies, enhanced proliferative capabilities, and suitability for high-passage applications.
• Stem Cells: Ethnic- and gender-diverse induced pluripotent stem cells (iPSCs) derived from normal and diseased tissues, as well as adult human mesenchymal stem cells and mouse embryonic stem cells.
• Advanced Cell Models: Including isogenic cell lines with key oncogene mutations created using CRISPR/Cas9 technology, and luciferase-labeled cells for sensitive measurement of biological processes.
• Human Cancer Models Initiative (HCMI): Next-generation 2-D and 3-D patient-derived in vitro cancer models, including organoids, developed in collaboration with HCMI to advance cancer research and therapeutic development.

ATCC's commitment to rigorous quality control and cell authentication ensures that researchers receive credible cell cultures, leading to reproducible and reliable scientific results.

For more information, visit ATCC's Cell Products page.

Thousands of Authenticated Reference Genomes - ATCC Genome Portal

The ATCC Genome Portal (AGP) is the only authenticated reference genome database for ATCC microbes. We now have more than 5,250 genomes available on the AGP and continue to release additional genomes every quarter.

Access to ATCC Reference Genomes

Customers who have purchased an ATCC microbe are able to view and download the respective genome assembly at no additional charge . Detailed directions are available here . For researchers who want access to the entire database, we offer a supporting membership. With a supporting membership, customers have access to all the microbial genomes, annotations, access to our API for bulk downloads, and our custom Discrepancy Report feature. For more details about the AGP, please click here . If you have any questions or would like to provide us with feedback, please contact us at nextgen@atcc.org.

Next Generation Cancer Models

ATCC HCMI Cell Models

ATCC is excited to provide the HCMI models, which include both common as well as rare and understudied examples of cancer from numerous tissues. These HCMI models are valuable tools to study cancer, identify and target novel therapies, and facilitate translational cancer research. To enhance their clinical relevance, the sequence data and patient clinical information for each model is available to the research community. Explore the Collection

ATCC Organoid Growth Kit

Organoids are valuable tools to study cancer, identify and target novel therapies, and facilitate translational cancer research. These 3-D models are becoming more relevant because they are predictive of the in vivo tumor microenvironment. In efforts to simplify Organoid culture, ATCC has developed Organoid Growth Kits which comprise single-use supplements created to streamline media preparation. These kits contain the most costly and cumbersome supplements and reagents, reducing the time and effort required to prepare media and ensuring the successful growth of your organoids. Explore the Collection.

Reporter-labeled Cells

Reporter-labeled cell lines are invaluable research tools for studying gene expression and for screening cell lines. Some of the most commonly used reporter systems are those that induce a visually identifiable phenotype such as the emission of fluorescent or luminescent light or the production of a pigmented product. Fluorescent reporters exhibit a fluorescent signal upon exposure to specific wavelengths of light; luminescent reporters use a luciferase enzyme to catalyze a reaction with its substrate, luciferin, to produce visible light; and chromogenic reporters employ an enzyme label that reacts with a substrate to produce a pigmented product.

Discover more at: https://www.atcc.org/cell-products/reporter-labeled-cells

ATCC Cell Line Land Webinar

Enhance Your Research with the ATCC Cell Line Land Webinar

Unlock the full potential of your research with insights from the recorded webinar "ATCC Cell Line Land: Reference-Quality RNAseq Data from Credible ATCC Cell Lines".

In this comprehensive webinar, industry experts delve into:

• The Importance of Credible Cell Lines: Understand why using authentic ATCC cell lines is crucial for reliable research outcomes.
• Reliable and Authentic RNAseq Data: Learn how ATCC ensures the highest quality and reliability in their RNAseq data.
• Practical Applications: Discover how RNAseq data can be applied across various fields of study to enhance your research.

Watch the Webinar Recording:

Title: ATCC Cell Line Land: Reference-Quality RNAseq Data from Credible ATCC Cell Lines
Link: Watch the Recording

Don't miss this opportunity to learn from the best and leverage ATCC's trusted resources to take your research to the next level. Watch the recording today!

NEW Genomic DNA Control Materials for Measurement of Residual DNA - ATCC-USP Collaboration

Analytical Reference Materials for Residual Host Cell DNA Testing

Regulators require that manufacturers demonstrate the removal of genomic DNA from biological therapies and vaccines since it can pose a safety risk if it is not purified from the product. As biopharmaceutical innovation continues to advance, trusted reference materials and standards can help accelerate biologics development.

ATCC and USP have come together to offer solutions that help ensure the quality of cell and gene therapies, vaccines, and recombinant proteins. The initial set of six products consists of highly characterized and pure genomic DNA (gDNA) from cell lines used in bioproduction that can be used to measure residual host cell DNA.

These products and materials support the most common platforms used in the rapidly growing cell and gene therapy and vaccines sectors:

• Quantitative HEK-293 Genomic DNA
• Quantitative Sf9 Genomic DNA
• Quantitative Vero Genomic DNA
• Quantitative MDCK Genomic DNA
• Quantitative MRC-5 Genomic DNA
• Quantitative BHK-21 Genomic DNA

Click here to learn more about these high-quality reference materials.

For more about the ATCC-USP collaboration, visit here.

cGMP Mammalian Cell Banking and Biorepository

ATCC's cGMP cell banking and biorepository services are designed to meet rigorous clinical and commercial manufacturing standards. They provide end-to-end support, including cell line authentication, sterility testing, and mycoplasma testing, ensuring the integrity and reliability of biological materials. Their state-of-the-art facilities offer secure, long-term storage with controlled environments to maintain cell bank viability and stability.

ATCC also offers regulatory support and documentation, essential for FDA and EMA compliance. Their expert team facilitates the technical transfer of cell banks, ensuring a smooth transition to production phases. This comprehensive approach minimizes risks and accelerates the path to market.

Key features of ATCC’s services include:

• Development and storage of Master and Working Cell Banks with comprehensive characterization.
• Stringent quality control measures to uphold biopharmaceutical production standards.
• Advanced storage facilities ensuring cell bank stability.
• Regulatory compliance support for seamless FDA and EMA approval.

News

ATCC and USP Enter Strategic Collaboration to Support Global Quality Production of Biologics

Manassas, VA, February 2023 - ATCC and USP to provide solutions and standards to help customers deliver safe and high-quality biologics to patients more rapidly. ATCC, the world’s premier biological materials management and standards organization and U.S. Pharmacopeia (USP), an independent, international, and scientific nonprofit organization, today announced a long-term, multi-year strategic collaboration to jointly provide co-branded reference materials and reference standards that will serve to advance the quality and development of biologic medicines and therapies. Read more.

ATCC Announces Award from Leidos Biomedical Research for the Production and Distribution of Next-generation Cancer Models

January, 2022 — ATCC, the world’s premier biological materials management and standards organization, today announced that it has been awarded a contract with Leidos Biomedical Research, Inc. (Leidos Biomed), current operator of the Frederick National Laboratory for Cancer Research, for the continued production, characterization and distribution of next-generation cancer models (NGCM). These models will be distributed solely by ATCC as part of the National Cancer Institute’s (NCI) Human Cancer Model Initiative (HCMI), an international consortium that is generating novel, next-generation, tumor-derived culture models annotated with genomic, clinical and biospecimen data. In consultation with the HCMI team at Leidos Biomed and the Center for Cancer Genomics (CCG) at NCI, the contract will add 70 additional NGCMs to HCMI’s current catalog of 182 models – all of which will be available as a community resource through its data portal. Read more.