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  • R&D Systems is committed to delivering high quality reagents for all aspects of cell biology research, and has operated under this objective since its formation. R&D is dedicated to providing the highest quality in the manufacture, sale and support of its products. Product quality, compliance to all applicable regulatory requirements, consistent improvement and customer satisfaction are the fundamental initiatives underlying the operations of R&D Systems.

    As a division of Bio-Techne, R&D Systems functions alongside Tocris Bioscience and Boston Biochem as the primary flagship brands in Bio-Techne’s life science portfolio. This conjunction has allowed R&D to better serve its diverse and widespread customer base by providing high quality and performance products under a reliable brand name.

    Key Research Topics:

    • Cancer
    • Cytokines & Growth Factors
    • Developmental Biology
    • Endocrinology
    • Glycobiology
    • Immunology
    • Neuroscience
    • Proteases & Other Enzymes
    • Signal Transduction
    • Stem Cells
    • Ubiquitin, Related Modifiers & Pathways

    Product Categories

    Antibodies, Antibody Staining Kits & Reagents

    R&D Systems provides a wide array of over 10,000 high-quality primary and secondary antibodies, as well as a number of antibody staining kits and reagents. With a variety of species including human, mouse, rat, bovine and chicken, R&D Systems offers both monoclonal and polyclonal antibodies, as well as a variety of conjugates. These antibodies are available against (or for) cytokines, adhesion molecules, proteases, neurotrophic factors, stem cell factors, signal transduction molecules, and developmental proteins. Each antibody is manufactured under controlled conditions to ensure quality, consistency, low endotoxin levels and stability. R&D antibodies are also available in bulk pack sizes to meet researcher needs.

    Cell Selection Kits & Reagents, Flow Cytometry Kits

    R&D offers a variety of products for cell selection, including cell enrichment columns that use affinity negative selection and MagCellect™ Cell Selection kits that utilize ferrofluids (magnetic particles) for magnetic separation. R&D Systems cell selection kits incorporate flow cytometry kits for the assessment of receptor density and multi-color kits that can instantaneously measure a maximum of four separate target molecules.

    Cell Culture & Stem Cell Reagents

    R&D provides a wide array of specific tools for culturing and sustaining a multitude of cell types under serum and serum-free research parameters. Featured cell culture products include leukocyte differentiation and expansion kits, extracellular matrix pre-coated plates, and basement membrane extracts to encompass a variety of research applications. Similarly, R&D Systems wide-ranging stem cell product line includes cancer stem cells, neural stem cells and hematopoietic stem cells.

    ELISAs/Assays, ELISpot Kits & Development Modules, ELISA/Assay Development Kits & Reagents

    R&D Systems offers a number of thoroughly tested, high-quality complete ELISA kits available in multiple formats including colorimetric, fluorescence, and chemiluminescence for measuring intracellular and extracellular proteins. These kits are strenuously tested to ensure superior quality and reproducibility.

    R&D Systems ELIspot kits are highly sensitive, microplate-based assays for the detection of cytokine secreting cells. These kits require no assay development or refinement and are available as single analyte ELISpot Kits, Dual-Color ELISpot Kits or Dual-Color FluoroSpot Kits. Alternatively, R&D ELIspot Development Modules include the rudimentary elements necessary to developing ELISpot assays. These quality modules provide a cost-effective substitute to purchasing individual antibodies and proteins.

    Multiplex/Array Assay Kits & Reagents

    R&D multiplex assays are extremely efficient tools for measuring the levels of numerous proteins in a single sample. R&D offers many different assay formats for multi-analyte analysis, providing a great deal of flexibility to accommodate a variety of research needs and applications. Different varieties of multiplex assays/arrays include Bead-based Multiplex Kits for the Luminex® Platform, Microplate-based Multiplex Kits and Membrane-based Multiplex Kits.

    Ligand Set, Small Molecule, Screening Library, Peptides & Peptide-Based Assays

    R&D is a leading supplier of ligand sets, small molecule life science research tools, screening libraries, peptides and peptide-based assays. Small molecules have numerous research applications and benefits, as they can be designated to selective, potent, water soluble or cell permeable. R&D Systems is proud to offer high-quality small molecule research tools available for enzymes, transporters, cell biology and ligand sets.

    Peptides are chains formed of primarily α-amino acids linked by amide bonds, and are distinguished from proteins on the basis of size. A number of peptides are present in all living organisms and execute a variety of essential biological functions. R&D Systems offers a multitude of peptides, which are available by pharmacological activity and have a broad range of applications.

    R&D also offers a number of ligand sets, which are essential products in the realm of life science research. Ligand sets are comprised of 3-5 essential ligands supplied as lyophilized solids, or pre-dissolved in DMSO at a particular concentration. These sets are developed to allow specific targeting or receptors or pathways in an economical fashion.

    Recombinant & Natural Proteins

    R&D is the leading global source of premier recombinant proteins. This extensive product line includes recombinant and natural proteins that are tested on a consistent basis to ensure quality, purity and consistency. R&D also caters to large research facilities and programs by offering bulk protein orders without sacrificing quality or purity.

    Versa Clone cDNA/Primer Pairs

    R&D Systems offers a wide range of companion genetic products, including a number of VersaClone cDNA, as well as PCR primer pairs. All of these products are carefully tested to ensure quality and consistency.

    Ubiquitin Proteasome Pathway (UPP) Assay Kits & Reagents: Proteasome Enzymes, Proteasome Inhibitors, E1 Activating Enzymes, E2 Conjugating Enzymes, Conjugation Control Proteins & Peptides, Deconjugating Enzyme Substrates

    R&D Systems provides an extensive range of ubiquitin proteasome pathway assay kits and reagents. Degradation of a protein via the Ubiquitin Proteasome pathway involves two separate and successive steps: tagging of the substrate protein by the covalent attachment of multiple Ubiquitin molecules (conjugation), and the subsequent degradation of the tagged protein by the 26s proteasome. There are three key conjugation enzymes (E1, E2, E3) that function in a hierarchical system and allow Ubiquitin to be activated and become covalently linked to protein substrates.

    R&D Systems provides a comprehensive range of deconjugating enzyme substrate products, representing an area of research with a high potential. Deconjugating enzymes are an essential class of enzymes and R&D Systems product line reflects this important role by providing high-quality and performance deconjugating enzymes, available with E. coli as their primary protein source.

    Supplemental reagents: Affinity Matrices, Autophagy Reagents, Supplemental Kits & Reagents, Buffers, Solutions & Standards

    As a subset of recombinant proteins, R&D Systems offers a wide array of affinity matrix products for depletion of high abundance serum and plasma proteins from human samples. These products are strenuously and consistently tested to ensure that the quality, purity and performativity standards of researchers are met.

    R&D Systems offers a number of high-quality and performance products relevant for the research of autophagy-related proteins. Autophagy occupies a significant role in development, aging, immunity and cell death and in human has been connected with cancer, neurodegeneration and various muscular diseases. The three primary forms of autophagy: macroautophagy (the most common), microautophagy and chaperone-mediated autophagy are all accounted for in this diverse range of R&D products.

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